Comix Zone is a game in which the player is a comic book artist named Sketch Turner, who is trapped inside his own comic book and must move and fight through panel to panel. He is able to use the environment to his advantage by knocking explosive boxes at enemies, or by ripping a piece of paper and turning it into a deadly paper plane. Sketch has a trusty sidekick in the form of his pet rat, Roadkill. Roadkill has the ability to stun enemies and can help find hidden items/solve puzzles. Sketch isn't limited to fighting with his bare hands though; he can pick up various items throughout the game such as bombs, grenades, knives and more. The game takes place across three episodes (split into two parts) and each episode ends with a boss fight. The game features multiple endings based solely around the outcome of the final fight with Mortus.
Comix Zone is considered to be a cult-classic for it's unique comic book concept and style. It was released rather late in the Genesis's life cycle and because of that it didn't sell well. It has more recently been re-released on the Wii's Virtual Console and as a part of both the Sega Genesis Collection (PS2/PSP) and Sonic's Ultimate Genesis Collection (360/PS3). Most recently the game was ported to XBLA as part of Sega's Vintage Compilation promotion.